Nafisa Abdullah was born and raised in Kabul, Afghanistan, and earned her medical degree from Kabul University in 1968. In 1969, she came to the United States and began her specialization in Obstetrics and Gynecology. Presently, she is an Executive Member of the Afghan Medical Association of America(AMAA) and a board member of the Afghan Women's Association of Southern California (AWASC).
After the U.S. invasion of Afghanistan, Dr. Abdullah made several trips to Afghanistan to share her skills as an Obstetrician/Gynecologist in various hospitals in Kabul, Panj Sheer and Mazare Sharief, including surgery and lectures in the field of Obstetrics and Gynecology. She continues to be active in the Southern California Afghan community raising funds for medical and educational efforts in Afghanistan. From 2004 to the present, she has been a volunteer, spokesperson, and board member for the Los Angeles Chapter of Emergency USA, an Italian humanitarian organization, which seeks to provide life support for civilian victims of war and poverty. From 1998 to 2003, she was a member of the Women’s Health Advisory Committee of Kaiser Permanente while also serving as director of the Education Program on Perimenopause and Menopause. She has also served as a board member for International Orphan Care (1993-2001).